Aswendt Lab · Frankfurt
Understanding stroke.
Advancing recovery.
We study how brain circuits change after experimental stroke and how neuromodulation can support recovery. Our work combines MRI, viral tracing, light sheet microscopy, and open analysis tools.
How we study recovery
Brain networks
We use MRI and circuit mapping to understand how structural and functional connections change after stroke.
Explore recovery research →Neuromodulation
We investigate motor deficits and stimulation approaches that support plasticity and functional recovery.
Explore neuromodulation →Open science
We build accessible imaging tools and FAIR workflows to make preclinical research more reproducible.
Discover software & data →The AIDA toolbox
Open tools for preclinical imaging
From MRI processing and quality control to atlas registration and connectivity analysis. Explore our tools, watch the animation, and find the code on GitHub.
Featured publication · 2026
Mapping connectivity after stroke
How do structural brain networks change after stroke? Our longitudinal study examines connectivity changes in mice with cortical and cortico-striatal strokes.
Mahani FSN et al. · Neural Regeneration Research · 2 citations in OpenAlex
Latest publications
All publications →article · 2026
Dynamic Functional Connectivity Changes in Cortical and Cortico-Striatal Strokes in Mice
CNS Neuroscience & Therapeutics
1 citations in OpenAlex
article · 2026
TrainTracks - federated learning for reproducible research on sensitive medical data
BMC Medical Informatics and Decision Making
0 citations in OpenAlex
article · 2026
Dynamic structural connectivity changes in cortical and cortico-striatal strokes in mice
Neural Regeneration Research
2 citations in OpenAlex
Latest news
All news →Connecting across Rhine-Main
The team joined the RMN² Retreat for scientific exchange with the regional neuroscience community.
Read the retreat update →CoBIC opens its doors
We celebrated the CoBIC Scientific Opening Symposium with presentations and discussions across brain research.
Read about the symposium →Motor control in focus
Julian, Motahare, and Markus shared project updates at the sixth CRC 1451 Annual Retreat.
Read the CRC 1451 update →Supported by
Collaboration partners
Our collaborators bring together expertise in neuroimaging, neuroscience, and reproducible research.
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Prof. Philipp Boehm-Sturm
Charité Berlin
Experimental Neurology · Berlin, Germany -
Prof. Maged Goubran
University of Toronto
Medical Biophysics · Toronto, Canada -
Prof. Michael Hanke
Research Center Jülich
INM-7 · Jülich, Germany -
Dr. Giovanna Ielacqua
Novartis
Novartis Institutes for Biomedical Research · Basel, Switzerland -
Dr. Christoph Leuze
Stanford University
School of Medicine, Radiology · Stanford, USA -
Prof. Milos Pekny & Prof. Marcela Pekna
University of Gothenburg
Clinical Neurosciences · Gothenburg, Sweden -
Prof. Adele Rüger & Prof. Lukas J. Volz
University Hospital Cologne
Department of Neurology · Cologne, Germany